› 2wqh

X-ray diffraction
2.2Å resolution

Crystal structure of CTPR3Y3

Released:
DOI: 10.2210/pdb2wqh/pdb
PDB entry 2wqh coloured by chain, front view.
PDB entry 2wqh coloured by chain, side view.
PDB entry 2wqh coloured by chain, top view.
Source organism: synthetic construct
Primary publication:
Self-association of TPR domains: Lessons learned from a designed, consensus-based TPR oligomer.
Krachler AM, Sharma A, Kleanthous C
Proteins 78 2131-43 (2010)
PMID: 20455268

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-163299 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CTPR3Y3 Chain: A
Molecule details ›
Chain: A
Length: 125 amino acids
Theoretical weight: 14.51 KDa
Source organism: synthetic construct
Structure domains: Tetratricopeptide repeat domain

Ligands and Environments

3 bound ligands:
Ligand MRD 1 x MRD
Ligand MPD 1 x MPD
Ligand EDO 2 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P6522
Unit cell:
a: 62.284Å b: 62.284Å c: 120.368Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.237 0.235 0.285

Quick links

Citations

4 review citations

Activities and regulation of peptidoglycan synthases.
Egan et al. (2015)
3 more

9 mentions without citation

Tetratricopeptide repeat motifs in the world of bacterial pathogens: role in virulence mechanisms.
Cerveny et al. (2013)
8 more