› 2wqf

X-ray diffraction
1.35Å resolution

Crystal Structure of the Nitroreductase CinD from Lactococcus lactis in Complex with FMN

Released:
DOI: 10.2210/pdb2wqf/pdb
PDB 2wqf coloured by chain and viewed from the front.
PDB 2wqf coloured by chain and viewed from the side.
PDB 2wqf coloured by chain and viewed from the top.
Source organism: Lactococcus lactis
Primary publication:
Structure and function of CinD (YtjD) of Lactococcus lactis, a copper-induced nitroreductase involved in defense against oxidative stress.
Mermod M, Mourlane F, Waltersperger S, Oberholzer AE, Baumann U, Solioz M
J. Bacteriol. 192 4172-80 (2010)
PMID: 20562311

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nitroreductase domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 202 amino acids
Theoretical weight: 22.56 KDa
Source organism: Lactococcus lactis
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9CED0 (Residues: 1-202; Coverage: 100%)
Gene names: L174788, ytjD
Sequence domains: Nitroreductase family
Structure domains: NADH Oxidase

Ligands and Environments

1 bound ligand:
Ligand FMN 1 x FMN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06DA
Spacegroup: C2221
Unit cell:
a: 53.843Å b: 120.147Å c: 68.659Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.132 0.132 0.156
Expression system: Escherichia coli

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Citations

2 review citations

Oxygen Sensing, Hypoxia Tracing and in Vivo Imaging with Functional Metalloprobes for the Early Detection of Non-communicable Diseases.
Mirabello et al. (2018)
1 more

3 mentions without citation

Structure and function of CinD (YtjD) of Lactococcus lactis, a copper-induced nitroreductase involved in defense against oxidative stress.
Mermod et al. (2010)
2 more