X-ray diffraction
2.7Å resolution

HCMV protease inhibitor complex


Function and Biology Details

Reaction catalysed:
Cleaves -Ala-|-Ser- and -Ala-|-Ala- bonds in the scaffold protein.
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Assemblin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 256 amino acids
Theoretical weight: 28.18 KDa
Source organism: Human betaherpesvirus 5
Expression system: Escherichia coli
  • Canonical: P16753 (Residues: 1-256; Coverage: 36%)
Gene names: APNG, UL80
Structure domains: Herpesvirus/Caudovirus protease domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Unit cell:
a: 107.8Å b: 53.4Å c: 212.4Å
α: 90° β: 90° γ: 90°
R R work R free
0.226 0.226 0.332
Expression system: Escherichia coli