Function and Biology Details
Reaction catalysed:
Selective cleavage of Arg-|-Ile bond in factor X to form factor Xa.
Biochemical function:
Biological process:
Cellular component:
- not assigned
Structure analysis Details
Assembly composition:
hetero trimer (preferred)
Assembly name:
Coagulation factor IXa complex and peptide (preferred)
PDBe Complex ID:
PDB-CPX-133193 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
Coagulation factor IXa light chain
Molecule details ›
Chain: E
Length: 59 amino acids
Theoretical weight: 6.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Coagulation Factor Xa inhibitory site
Structure domains: Laminin
Length: 59 amino acids
Theoretical weight: 6.5 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P00740 (Residues: 133-191; Coverage: 14%)
Sequence domains: Coagulation Factor Xa inhibitory site
Structure domains: Laminin
Coagulation factor IXa heavy chain
Molecule details ›
Chain: S
Length: 235 amino acids
Theoretical weight: 26.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
Length: 235 amino acids
Theoretical weight: 26.08 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P00740 (Residues: 227-461; Coverage: 54%)
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
