PDBe 2wow

X-ray diffraction
2.2Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Trypanothione reductase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 495 amino acids
Theoretical weight: 53.5 KDa
Source organism: Trypanosoma brucei brucei TREU927
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Best match: Q389T8 (Residues: 1-492)
Gene name: Tb10.406.0520

Ligands and Environments


Cofactor: Ligand FAD 4 x FAD

Cofactor: Ligand NDP 4 x NDP
1 bound ligand:

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: P21
Unit cell:
a: 101.7Å b: 63.7Å c: 169.6Å
α: 90° β: 97.6° γ: 90°
R-values:
R R work R free
0.175 0.172 0.226
Expression system: Escherichia coli BL21(DE3)