X-ray diffraction
2.2Å resolution

Crystal structure of Aplysia ACHBP in complex with tropisetron

Source organism: Aplysia californica
Entry authors: Sulzenbacher G, Hibbs R, Shi J, Talley T, Conrod S, Kem W, Taylor P, Marchot P, Bourne Y

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Neur_chan_LBD domain-containing protein Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 227 amino acids
Theoretical weight: 25.85 KDa
Source organism: Aplysia californica
Expression system: Homo sapiens
  • Canonical: Q8WSF8 (Residues: 18-236; Coverage: 100%)
Sequence domains: Neurotransmitter-gated ion-channel ligand binding domain
Structure domains: Neurotransmitter-gated ion-channel ligand-binding domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: I23
Unit cell:
a: 212.584Å b: 212.584Å c: 212.584Å
α: 90° β: 90° γ: 90°
R R work R free
0.178 0.177 0.212
Expression system: Homo sapiens