X-ray diffraction
2.4Å resolution

Chitinase A from Serratia marcescens ATCC990 in complex with Chitotrio-thiazoline.

Source organism: Serratia marcescens
Primary publication:
Chitinase inhibition by chitobiose and chitotriose thiazolines.
Angew. Chem. Int. Ed. Engl. 49 2599-602 (2010)
PMID: 20209544

Function and Biology Details

Reaction catalysed:
Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins
Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Chitinase A Chain: A
Molecule details ›
Chain: A
Length: 548 amino acids
Theoretical weight: 59.76 KDa
Source organism: Serratia marcescens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P07254 (Residues: 24-541; Coverage: 96%)
Gene name: chiA
Structure domains:

Ligands and Environments

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: C2221
Unit cell:
a: 131.004Å b: 201.442Å c: 59.325Å
α: 90° β: 90° γ: 90°
R R work R free
0.158 0.155 0.205
Expression system: Escherichia coli BL21(DE3)