PDBe 2wko

X-ray diffraction
1.97Å resolution

Structure of metal loaded Pathogenic SOD1 Mutant G93A.

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Superoxide dismutase [Cu-Zn] Chain: A
Molecule details ›
Chain: A
Length: 154 amino acids
Theoretical weight: 15.87 KDa
Source organism: Homo sapiens
Expression system: Saccharomyces cerevisiae
UniProt:
  • Best match: P00441 (Residues: 2-154)
Gene name: SOD1
Superoxide dismutase [Cu-Zn] Chain: F
Molecule details ›
Chain: F
Length: 154 amino acids
Theoretical weight: 15.88 KDa
Source organism: Homo sapiens
Expression system: Saccharomyces cerevisiae
UniProt:
  • Best match: P00441 (Residues: 2-154)
Gene name: SOD1

Ligands and Environments

3 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.6
Spacegroup: P21
Unit cell:
a: 51.488Å b: 47.157Å c: 56.356Å
α: 90° β: 90.38° γ: 90°
R-values:
R R work R free
0.177 0.174 0.231
Expression system: Saccharomyces cerevisiae