2wju

X-ray diffraction
2.3Å resolution

Glutathione transferase A2-2 in complex with glutathione

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Glutathione S-transferase A2 Chains: A, B, C, D, E, F, G, H
Molecule details ›
Chains: A, B, C, D, E, F, G, H
Length: 222 amino acids
Theoretical weight: 25.72 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P09210 (Residues: 1-222; Coverage: 100%)
Gene names: GST2, GSTA2
Sequence domains: Glutathione S-transferase, N-terminal domain
Structure domains:

Ligands and Environments


Cofactor: Ligand GSH 8 x GSH
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-1
Spacegroup: P1
Unit cell:
a: 54.16Å b: 85.5Å c: 113.42Å
α: 96° β: 101.78° γ: 97.46°
R-values:
R R work R free
0.248 0.246 0.297
Expression system: Escherichia coli