Structure analysis

Interaction of Mycobacterium tuberculosis CYP130 with heterocyclic arylamines

X-ray diffraction
1.58Å resolution
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule


Assembly 1 (preferred)
Download    3D Visualisation
Multimeric state: monomeric
Accessible surface area: 16000 Å2
Buried surface area: 2400 Å2
Dissociation area: 300 Å2
Dissociation energy (ΔGdiss): -6 kcal/mol
Dissociation entropy (TΔSdiss): 3 kcal/mol
Interface energy (ΔGint): -20 kcal/mol
Symmetry number: 1


Chain: A
Length: 413 amino acids
Theoretical weight: 45.71 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P9WPN5 (Residues: 2-405; Coverage: 100%)
Gene names: MTCY50.26, Rv1256c, cyp130
Pfam: Cytochrome P450
CATH: Cytochrome P450

Search similar proteins