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Crystal Structure of Tip-Alpha N34 (HP0596) from Helicobacter pylori at pH4

X-ray diffraction
1.9Å resolution
PDB entry 2wcq coloured by chain, front view.
PDB entry 2wcq coloured by chain, side view.
PDB entry 2wcq coloured by chain, top view.
Source organism: Helicobacter pylori
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Tumor necrosis factor alpha-inducing protein
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-127744
Assembly 2
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Assembly Name: Tumor necrosis factor alpha-inducing protein
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-127744

Macromolecules

Tumor necrosis factor alpha-inducing protein
Chains: A, B
Length: 159 amino acids
Theoretical weight: 18.23 KDa
Source organism: Helicobacter pylori
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: O25318 (Residues: 34-192; Coverage: 83%)
Gene name: HP_0596
Pfam: TNF-alpha-Inducing protein of Helicobacter
InterPro: Helicobacter TNF-alpha-inducing protein
CATH: Helicobacter TNF-alpha-Inducing protein
Tumor necrosis factor alpha-inducing protein in PDB entry 2wcq, assembly 1, front view.
Tumor necrosis factor alpha-inducing protein in PDB entry 2wcq, assembly 1, side view.
Tumor necrosis factor alpha-inducing protein in PDB entry 2wcq, assembly 1, top view.
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