› 2wbh

X-ray diffraction
4.7Å resolution

Icosahedral particle of covalent coat protein dimer of bacteriophage MS2

Released:
DOI: 10.2210/pdb2wbh/pdb
PDB entry 2wbh coloured by chain, front view.
PDB entry 2wbh coloured by chain, side view.
PDB entry 2wbh coloured by chain, top view.
Source organism: Escherichia virus MS2
Primary publication:
Structure and stability of icosahedral particles of a covalent coat protein dimer of bacteriophage MS2.
Plevka P, Tars K, Liljas L
Protein Sci 18 1653-61 (2009)
PMID: 19521994

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo 180-mer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137135 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Capsid protein Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 257 amino acids
Theoretical weight: 27.37 KDa
Source organism: Escherichia virus MS2
Expression system: Escherichia coli
UniProt:
  • Canonical: P03612 (Residues: 2-130; Coverage: 99%)
Sequence domains: Levivirus coat protein

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID29
Spacegroup: P213
Unit cell:
a: 368.2Å b: 368.2Å c: 368.2Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.318 0.318 not available
Expression system: Escherichia coli

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Citations

4 review citations

Virus-like particles: Next-generation nanoparticles for targeted therapeutic delivery.
Rohovie et al. (2017)
3 more

2 mentions without citation

Virus-like Particle-Based L2 Vaccines against HPVs: Where Are We Today?
Yadav et al. (2019)
1 more