2wal

X-ray diffraction
2.4Å resolution

Crystal Structure of human GADD45gamma

Released:
Source organism: Homo sapiens
Entry authors: Bhattacharya S, Mueller JJ, Roske Y, Turnbull AP, Quedenau C, Goetz F, Buessow K, Heinemann U

Function and Biology Details

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Growth arrest and DNA damage-inducible protein GADD45 gamma Chains: A, B
Molecule details ›
Chains: A, B
Length: 159 amino acids
Theoretical weight: 17.1 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O95257 (Residues: 1-159; Coverage: 100%)
Gene names: CR6, DDIT2, GADD45G
Sequence domains: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family
Structure domains: 60s Ribosomal Protein L30; Chain: A;

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: P3221
Unit cell:
a: 108.717Å b: 108.717Å c: 73.371Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.216 0.215 0.251
Expression system: Escherichia coli BL21(DE3)