PDBe 2vxp

X-ray diffraction
2.5Å resolution

The fourth FAS1 domain structure of human Bigh3

Released:
Source organism: Homo sapiens
Entry authors: Yoo J-H, Cho H-S

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transforming growth factor-beta-induced protein ig-h3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 132 amino acids
Theoretical weight: 14.26 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q15582 (Residues: 502-633; Coverage: 20%)
Gene names: BIGH3, TGFBI
Structure domains: FAS1 domain

Ligands and Environments

No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PAL/PLS BEAMLINE 4A
Spacegroup: P65
Unit cell:
a: 62.934Å b: 62.934Å c: 143.29Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.27 0.27 0.285
Expression system: Escherichia coli BL21(DE3)