PDBe 2vsc

X-ray diffraction
1.9Å resolution

Structure of the immunoglobulin-superfamily ectodomain of human CD47

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Leukocyte surface antigen CD47 Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 127 amino acids
Theoretical weight: 14.52 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: Q08722 (Residues: 19-136; Coverage: 39%)
Gene names: CD47, MER6
Structure domains: Immunoglobulins

Ligands and Environments

2 bound ligands:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: C2
Unit cell:
a: 201.137Å b: 47.502Å c: 56.811Å
α: 90° β: 99.31° γ: 90°
R-values:
R R work R free
0.219 0.216 0.263
Expression system: Cricetulus griseus