2vpj

X-ray diffraction
1.85Å resolution

Crystal structure of the Kelch domain of human KLHL12

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kelch-like protein 12 Chain: A
Molecule details ›
Chain: A
Length: 301 amino acids
Theoretical weight: 32.91 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q53G59 (Residues: 267-567; Coverage: 53%)
Gene names: C3IP1, KLHL12
Structure domains: Kelch-type beta propeller

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P21
Unit cell:
a: 44.637Å b: 61.546Å c: 45.523Å
α: 90° β: 111.75° γ: 90°
R-values:
R R work R free
0.164 0.161 0.222
Expression system: Escherichia coli BL21(DE3)