Function and Biology

Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex

Source organism: Homo sapiens
Biochemical function: beta-catenin binding
Biological process: canonical Wnt signaling pathway
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00628
Domain description: PHD-finger
Occurring in:
  1. Pygopus homolog 1
The deposited structure of PDB entry 2vpe contains 2 copies of Pfam domain PF00628 (PHD-finger) in Pygopus homolog 1. Showing 1 copy in chain C.

InterPro InterPro annotations
IPR019787
Domain description: Zinc finger, PHD-finger
Occurring in:
  1. Pygopus homolog 1
IPR013083
Domain description: Zinc finger, RING/FYVE/PHD-type
Occurring in:
  1. Pygopus homolog 1
  2. B-cell CLL/lymphoma 9 protein
IPR015668
Domain description: B Cell Lymphoma 9
Occurring in:
  1. B-cell CLL/lymphoma 9 protein
IPR019786
Domain description: Zinc finger, PHD-type, conserved site
Occurring in:
  1. Pygopus homolog 1
IPR001965
Domain description: Zinc finger, PHD-type
Occurring in:
  1. Pygopus homolog 1
IPR011011
Domain description: Zinc finger, FYVE/PHD-type
Occurring in:
  1. Pygopus homolog 1

Structure domain

CATH CATH domain
3.30.40.10
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Herpes Virus-1
Homology: Zinc/RING finger domain, C3HC4 (zinc finger)
Occurring in:
  1. Pygopus homolog 1
The deposited structure of PDB entry 2vpe contains 2 copies of CATH domain 3.30.40.10 (Herpes Virus-1) in Pygopus homolog 1. Showing 1 copy in chain C.