X-ray diffraction
2.1Å resolution

Crystal structure of N-terminal domains of Human La protein complexed with RNA oligomer AUAUUUU


Function and Biology Details

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
1 distinct RNA molecule
Macromolecules (2 distinct):
Lupus La protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 193 amino acids
Theoretical weight: 22.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P05455 (Residues: 4-194; Coverage: 47%)
Gene name: SSB
Sequence domains:
Structure domains:
5'-R(*AP*UP*AP*UP*UP*UP*UP)-3' Chains: C, D
Molecule details ›
Chains: C, D
Length: 7 nucleotides
Theoretical weight: 2.14 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: C2
Unit cell:
a: 140.029Å b: 44.471Å c: 91.285Å
α: 90° β: 114.35° γ: 90°
R R work R free
0.232 0.232 0.272
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided