X-ray diffraction
1.9Å resolution

X-ray crystal structure of 5'-fluorodeoxyadenosine synthase s158g mutant complexed with 5'-fluorodeoxyadenosin

Source organism: Streptomyces cattleya
Primary publication:
Mechanism of enzymatic fluorination in Streptomyces cattleya.
J Am Chem Soc 129 14597-604 (2007)
PMID: 17985882

Function and Biology Details

Structure analysis Details

Assembly composition:
homo hexamer (preferred)
Entry contents:
1 distinct polypeptide molecule
5'-fluoro-5'-deoxy-adenosine synthase Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 299 amino acids
Theoretical weight: 32.37 KDa
Source organism: Streptomyces cattleya
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q70GK9 (Residues: 1-299; Coverage: 100%)
Gene name: flA
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-2
Spacegroup: C2221
Unit cell:
a: 75.854Å b: 129.256Å c: 184.485Å
α: 90° β: 90° γ: 90°
R R work R free
0.189 0.187 0.221
Expression system: Escherichia coli BL21(DE3)