› 2v7l

X-ray diffraction
2.4Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-161160 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Monodechloroaminopyrrolnitrin synthase PrnB Chain: A
Molecule details ›
Chain: A
Length: 361 amino acids
Theoretical weight: 39.92 KDa
Source organism: Pseudomonas fluorescens
Expression system: Pseudomonas fluorescens
UniProt:
  • Canonical: P95481 (Residues: 1-361; Coverage: 100%)
Gene name: prnB
Sequence domains: Monodechloroaminopyrrolnitrin synthase PrnB
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand HEM 1 x HEM
Ligand CTE 1 x CTE
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU MICROMAX-007
Spacegroup: C2
Unit cell:
a: 68.41Å b: 78.883Å c: 93.341Å
α: 90° β: 104.11° γ: 90°
R-values:
R R work R free
0.184 0.182 0.213
Expression system: Pseudomonas fluorescens

Quick links

Citations

3 review citations

Tryptophan-kynurenine pathway is dysregulated in inflammation, and immune activation.
Wang et al. (2015)
2 more

1 mention without citation

The second enzyme in pyrrolnitrin biosynthetic pathway is related to the heme-dependent dioxygenase superfamily.
De Laurentis et al. (2007)