X-ray diffraction
1.7Å resolution

Structure of vaccinia-related kinase 2


Function and Biology Details

Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Serine/threonine-protein kinase VRK2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 345 amino acids
Theoretical weight: 39.26 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: Q86Y07 (Residues: 14-335; Coverage: 63%)
  • Best match: Q86Y07-3 (Residues: 1-312)
Gene name: VRK2
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P21212
Unit cell:
a: 70.655Å b: 157.532Å c: 56.288Å
α: 90° β: 90° γ: 90°
R R work R free
0.203 0.201 0.236
Expression system: Escherichia coli BL21(DE3)