Function and Biology

Structure of MAL-RPEL1 complexed to actin

Source organisms:
Biochemical function: cytoskeletal motor activator activity
Biological process: mesenchyme migration
Cellular component: skeletal muscle myofibril

Sequence families

Pfam Protein families (Pfam)
PF02755
Domain description: RPEL repeat
Occurring in:
  1. Myocardin-related transcription factor A
The deposited structure of PDB entry 2v51 contains 2 copies of Pfam domain PF02755 (RPEL repeat) in Myocardin-related transcription factor A. Showing 1 copy in chain C [auth E].

PF00022
Domain description: Actin
Occurring in:
  1. Actin, alpha skeletal muscle
The deposited structure of PDB entry 2v51 contains 2 copies of Pfam domain PF00022 (Actin) in Actin, alpha skeletal muscle. Showing 1 copy in chain B [auth D].

InterPro InterPro annotations
IPR004000
Domain description: Actin family
Occurring in:
  1. Actin, alpha skeletal muscle
IPR004018
Domain description: RPEL repeat
Occurring in:
  1. Myocardin-related transcription factor A
IPR004001
Domain description: Actin, conserved site
Occurring in:
  1. Actin, alpha skeletal muscle
IPR043129
Domain description: ATPase, nucleotide binding domain
Occurring in:
  1. Actin, alpha skeletal muscle
IPR043451
Domain description: Myocardin-like
Occurring in:
  1. Myocardin-related transcription factor A
IPR020902
Domain description: Actin/actin-like conserved site
Occurring in:
  1. Actin, alpha skeletal muscle

Structure domains

CATH CATH domains
3.30.420.40
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Nucleotidyltransferase; domain 5
Homology: Nucleotidyltransferase; domain 5
Occurring in:
  1. Actin, alpha skeletal muscle
The deposited structure of PDB entry 2v51 contains 4 copies of CATH domain 3.30.420.40 (Nucleotidyltransferase; domain 5) in Actin, alpha skeletal muscle. Showing 2 copies in chain B [auth D].
3.90.640.10
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: Actin; Chain A, domain 4
Homology: Actin; Chain A, domain 4
Occurring in:
  1. Actin, alpha skeletal muscle
The deposited structure of PDB entry 2v51 contains 2 copies of CATH domain 3.90.640.10 (Actin; Chain A, domain 4) in Actin, alpha skeletal muscle. Showing 1 copy in chain B [auth D].