X-ray diffraction
1.46Å resolution

Crystal structure of CYP130 from Mycobacterium tuberculosis in the ligand-free form


Function and Biology Details

Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Cytochrome P450 130 Chain: A
Molecule details ›
Chain: A
Length: 414 amino acids
Theoretical weight: 45.84 KDa
Source organism: Mycobacterium tuberculosis H37Rv
Expression system: Escherichia coli BL21
  • Canonical: P9WPN5 (Residues: 1-405; Coverage: 100%)
Gene names: MTCY50.26, Rv1256c, cyp130
Sequence domains: Cytochrome P450
Structure domains: Cytochrome P450

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID, ALS BEAMLINE 8.3.1
Spacegroup: C2
Unit cell:
a: 160.005Å b: 53.854Å c: 43.726Å
α: 90° β: 96.49° γ: 90°
R R work R free
0.199 0.196 0.227
Expression system: Escherichia coli BL21