› 2trx

X-ray diffraction
1.68Å resolution

CRYSTAL STRUCTURE OF THIOREDOXIN FROM ESCHERICHIA COLI AT 1.68 ANGSTROMS RESOLUTION

Released:
DOI: 10.2210/pdb2trx/pdb
PDB entry 2trx coloured by chain, front view.
PDB entry 2trx coloured by chain, side view.
PDB entry 2trx coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
Crystal structure of thioredoxin from Escherichia coli at 1.68 A resolution.
Katti SK, LeMaster DM, Eklund H
J Mol Biol 212 167-84 (1990)
PMID: 2181145

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-141959 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 108 amino acids
Theoretical weight: 11.69 KDa
Source organism: Escherichia coli
Expression system: Not provided
UniProt:
  • Canonical: P0AA25 (Residues: 2-109; Coverage: 99%)
Gene names: JW5856, b3781, fipA, trxA, tsnC
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

2 bound ligands:
Ligand CU 2 x CU
Ligand MPD 7 x MPD
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: C2
Unit cell:
a: 89.5Å b: 51.06Å c: 60.45Å
α: 90° β: 113.5° γ: 90°
R-values:
R R work R free
0.165 not available not available
Expression system: Not provided

Quick links

Citations

35 review citations

Structure, function and evolution of glutathione transferases: implications for classification of non-mammalian members of an ancient enzyme superfamily.
Sheehan et al. (2001)
34 more

101 mentions without citation

Reactivity of thioredoxin as a protein thiol-disulfide oxidoreductase.
Cheng et al. (2011)
100 more