2tmp

Solution NMR

N-TERMINAL DOMAIN OF TISSUE INHIBITOR OF METALLOPROTEINASE-2 (N-TIMP-2), NMR, 49 STRUCTURES

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Metalloproteinase inhibitor 2 Chain: A
Molecule details ›
Chain: A
Length: 127 amino acids
Theoretical weight: 14.11 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P16035 (Residues: 27-153; Coverage: 66%)
Gene name: TIMP2
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: SIMULATED ANNEALING USING TORSION ANGLE DYNAMICS
Chemical shifts: BMR4214  
Expression system: Escherichia coli BL21(DE3)