› 2tir

X-ray diffraction
2Å resolution

CRYSTAL STRUCTURE ANALYSIS OF A MUTANT ESCHERICHIA COLI THIOREDOXIN IN WHICH LYSINE 36 IS REPLACED BY GLUTAMIC ACID

Released:
DOI: 10.2210/pdb2tir/pdb
PDB entry 2tir coloured by chain, front view.
PDB entry 2tir coloured by chain, side view.
PDB entry 2tir coloured by chain, top view.
Source organism: Escherichia coli
Primary publication:
Crystal structure analysis of a mutant Escherichia coli thioredoxin in which lysine 36 is replaced by glutamic acid.
Nikkola M, Gleason FK, Fuchs JA, Eklund H
Biochemistry 32 5093-8 (1993)
PMID: 8098620

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-141959 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thioredoxin 1 Chain: A
Molecule details ›
Chain: A
Length: 108 amino acids
Theoretical weight: 11.69 KDa
Source organism: Escherichia coli
Expression system: Not provided
UniProt:
  • Canonical: P0AA25 (Residues: 2-109; Coverage: 99%)
Gene names: JW5856, b3781, fipA, trxA, tsnC
Sequence domains: Thioredoxin
Structure domains: Glutaredoxin

Ligands and Environments

1 bound ligand:
Ligand CU 1 x CU
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 50.8Å b: 26.8Å c: 80.7Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.199 0.199 not available
Expression system: Not provided

Quick links

Citations

1 review citation

Genetic map of Salmonella typhimurium, edition VIII.
Sanderson et al. (1995)
6 other articles

8 mentions without citation

Protein-protein docking benchmark version 4.0.
Hwang et al. (2010)
7 more