2rvb

Solution NMR

Solution structure of the complex between XPC acidic domain and TFIIH p62 PH domain

Released:

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
DNA repair protein complementing XP-C cells Chain: A
Molecule details ›
Chain: A
Length: 52 amino acids
Theoretical weight: 5.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q01831 (Residues: 109-156; Coverage: 5%)
Gene names: XPC, XPCC
General transcription factor IIH subunit 1 Chain: B
Molecule details ›
Chain: B
Length: 110 amino acids
Theoretical weight: 12.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P32780 (Residues: 1-108; Coverage: 20%)
Gene names: BTF2, GTF2H1
Sequence domains: TFIIH p62 subunit, N-terminal domain
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 89%
Refinement method: DGSA-distance geometry simulated annealing
Chemical shifts: BMR11594  
Expression system: Escherichia coli