Solution NMR

Interplay between phosphatidyl-inositol-phosphates and claudins upon binding to the 1st PDZ domain of zonula occludens 1

Source organism: Mus musculus

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Tight junction protein ZO-1 Chain: A
Molecule details ›
Chain: A
Length: 100 amino acids
Theoretical weight: 10.82 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
  • Canonical: P39447 (Residues: 18-110; Coverage: 5%)
Gene names: Tjp1, Zo1
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 82%
Refinement method: simulated annealing
Chemical shifts: BMR11424  
Expression system: Escherichia coli