› 2rnb

Solution NMR

Solution structure of human Cu(I)Cox17

Released:
DOI: 10.2210/pdb2rnb/pdb
PDB entry 2rnb coloured by chain, ensemble of 20 models, front view.
PDB entry 2rnb coloured by chain, ensemble of 20 models, side view.
PDB entry 2rnb coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
A structural-dynamical characterization of human Cox17.
Banci L, Bertini I, Ciofi-Baffoni S, Janicka A, Martinelli M, Kozlowski H, Palumaa P
J Biol Chem 283 7912-20 (2008)
PMID: 18093982

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171903 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytochrome c oxidase copper chaperone Chain: A
Molecule details ›
Chain: A
Length: 67 amino acids
Theoretical weight: 7.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14061 (Residues: 1-63; Coverage: 100%)
Gene name: COX17
Sequence domains: Cytochrome C oxidase copper chaperone (COX17)
Structure domains: CytochromE C oxidase copper chaperone

Ligands and Environments

1 bound ligand:
Ligand CU1 1 x CU1
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 83%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

18 review citations

Metabolism and functions of copper in brain.
Scheiber et al. (2014)
17 more

5 mentions without citation

Copper metallochaperones.
Robinson et al. (2010)
4 more