› 2rgo

X-ray diffraction
2.4Å resolution

Structure of Alpha-Glycerophosphate Oxidase from Streptococcus sp.: A Template for the Mitochondrial Alpha-Glycerophosphate Dehydrogenase

Released:
DOI: 10.2210/pdb2rgo/pdb
PDB entry 2rgo coloured by chain, front view.
PDB entry 2rgo coloured by chain, side view.
PDB entry 2rgo coloured by chain, top view.
Source organism: Streptococcus sp.
Primary publication:
Structure of alpha-glycerophosphate oxidase from Streptococcus sp.: a template for the mitochondrial alpha-glycerophosphate dehydrogenase.
Colussi T, Parsonage D, Boles W, Matsuoka T, Mallett TC, Karplus PA, Claiborne A
Biochemistry 47 965-77 (2008)
PMID: 18154320

Function and Biology Details

Reaction catalysed: 
sn-glycerol 3-phosphate + O(2) = glycerone phosphate + H(2)O(2)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assemblies composition:
homo dimer
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-112058 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Alpha-glycerophosphate oxidase Chains: A, B
Molecule details ›
Chains: A, B
Length: 607 amino acids
Theoretical weight: 67.66 KDa
Source organism: Streptococcus sp.
Expression system: Escherichia coli
UniProt:
  • Canonical: D0VWP7 (Residues: 1-607; Coverage: 100%)
Gene name: glpO
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand FAD 2 x FAD
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: P21
Unit cell:
a: 128.363Å b: 106.785Å c: 58.887Å
α: 90° β: 99.18° γ: 90°
R-values:
R R work R free
0.238 0.238 0.247
Expression system: Escherichia coli

Quick links

Citations

4 review citations

The function and the role of the mitochondrial glycerol-3-phosphate dehydrogenase in mammalian tissues.
Mráček et al. (2013)
3 more

2 mentions without citation

Assessing the accuracy of template-based structure prediction metaservers by comparison with structural genomics structures.
Gront et al. (2012)
1 more