Structure analysis

X-ray Structure of FXa in complex with 7-fluoroindazole

X-ray diffraction
2.3Å resolution
Source organism: Homo sapiens
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero dimer

Binding statistics and energies are not available for this assembly

Macromolecules

Chain: A
Length: 234 amino acids
Theoretical weight: 26.45 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P00742 (Residues: 235-468; Coverage: 51%)
Gene name: F10
Pfam: Trypsin
InterPro:
CATH: Trypsin-like serine proteases
SCOP: Eukaryotic proteases

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Chain: L
Length: 51 amino acids
Theoretical weight: 5.45 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P00742 (Residues: 129-178; Coverage: 11%)
Gene name: F10
Pfam: Coagulation Factor Xa inhibitory site
CATH: Laminin

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