X-ray diffraction
2.51Å resolution

Crystal structure of an I71V hGSTA1-1 mutant in complex with S-hexylglutathione

Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Glutathione S-transferase A1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 222 amino acids
Theoretical weight: 25.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
  • Canonical: P08263 (Residues: 1-222; Coverage: 100%)
Gene name: GSTA1
Sequence domains:
Structure domains:

Ligands and Environments

Cofactor: Ligand GTX 2 x GTX
No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU
Spacegroup: C2
Unit cell:
a: 98.409Å b: 93.577Å c: 50.717Å
α: 90° β: 93.05° γ: 90°
R R work R free
0.211 0.206 0.298
Expression system: Escherichia coli BL21(DE3)