Structure analysis

Crystal structure of the effector domain of human Plexin B1

X-ray diffraction
2Å resolution
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: homo dimer
Accessible surface area: 11800 Å2
Buried surface area: 2600 Å2
Dissociation area: 100 Å2
Dissociation energy (ΔGdiss): 12 kcal/mol
Dissociation entropy (TΔSdiss): -7 kcal/mol
Interface energy (ΔGint): -66 kcal/mol
Symmetry number: 2

Macromolecules

Chains: A, B
Length: 138 amino acids
Theoretical weight: 15.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O43157 (Residues: 1743-1862; Coverage: 6%)
Gene names: KIAA0407, PLXN5, PLXNB1, SEP
InterPro:
CATH: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

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