2r2o

X-ray diffraction
2Å resolution

Crystal structure of the effector domain of human Plexin B1

Released:

Function and Biology Details

Biochemical function:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Plexin-B1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 138 amino acids
Theoretical weight: 15.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O43157 (Residues: 1743-1862; Coverage: 6%)
Gene names: KIAA0407, PLXN5, PLXNB1, SEP
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Ligands and Environments

1 bound ligand:

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 23-ID-B, APS BEAMLINE 19-ID
Spacegroup: P212121
Unit cell:
a: 50.979Å b: 56.571Å c: 99.366Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.222 0.269
Expression system: Escherichia coli