Assemblies
Assembly Name:
Proprotein convertase subtilisin/kexin type 9
Multimeric state:
hetero dimer
Accessible surface area:
23964.1 Å2
Buried surface area:
2993.29 Å2
Dissociation area:
1,333.85
Å2
Dissociation energy (ΔGdiss):
13.48
kcal/mol
Dissociation entropy (TΔSdiss):
11.88
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-185469
Macromolecules
Chain: A
Length: 124 amino acids
Theoretical weight: 14.02 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Pfam: Peptidase inhibitor I9
InterPro:
Length: 124 amino acids
Theoretical weight: 14.02 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: Q8NBP7 (Residues: 29-152; Coverage: 18%)
Pfam: Peptidase inhibitor I9
InterPro:
- Peptidase S8 propeptide/proteinase inhibitor I9 superfamily
- Peptidase S8 propeptide/proteinase inhibitor I9
Chain: B
Length: 546 amino acids
Theoretical weight: 58.27 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
Pfam:
Length: 546 amino acids
Theoretical weight: 58.27 KDa
Source organism: Homo sapiens
Expression system: Homo sapiens
UniProt:
- Canonical: Q8NBP7 (Residues: 153-692; Coverage: 82%)
Pfam:
- Subtilase family
- Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain
- Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain
- Proprotein convertase subtilisin-like/kexin type 9 C-terminal domain
- Peptidase S8/S53 domain superfamily
- Proteinase K-like catalytic domain
- Peptidase S8, subtilisin-related
- Peptidase S8/S53 domain
- Proprotein convertase subtilisin/kexin type 9, C-terminal domain 1
- Proprotein convertase subtilisin/kexin type 9, C-terminal domain 2
- Proprotein convertase subtilisin/kexin type 9, C-terminal domain 3