› 2qkt

X-ray diffraction
2.05Å resolution

Crystal Structure of the 5th PDZ domain of InaD

Released:
DOI: 10.2210/pdb2qkt/pdb
PDB entry 2qkt coloured by chain, front view.
PDB entry 2qkt coloured by chain, side view.
PDB entry 2qkt coloured by chain, top view.
Source organism: Drosophila melanogaster
Primary publication:
Dynamic scaffolding in a G protein-coupled signaling system.
Mishra P, Socolich M, Wall MA, Graves J, Wang Z, Ranganathan R
Cell 131 80-92 (2007)
PMID: 17923089

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-173168 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Inactivation-no-after-potential D protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 90 amino acids
Theoretical weight: 9.71 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q24008 (Residues: 580-665; Coverage: 13%)
Gene names: CG3504, inaD
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: OTHER
Spacegroup: P41212
Unit cell:
a: 95.74Å b: 95.74Å c: 48.56Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.224 0.224 0.242
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

22 review citations

Sending signals dynamically.
Smock et al. (2009)
21 more

5 mentions without citation

Emerging Themes in PDZ Domain Signaling: Structure, Function, and Inhibition.
Liu et al. (2019)
4 more