› 2qg5

X-ray diffraction
2.3Å resolution

Cryptosporidium parvum calcium dependent protein kinase cgd7_1840

Released:
DOI: 10.2210/pdb2qg5/pdb
PDB 2qg5 coloured by chain and viewed from the front.
PDB 2qg5 coloured by chain and viewed from the side.
PDB 2qg5 coloured by chain and viewed from the top.
Source organism: Cryptosporidium parvum Iowa II
Entry authors: Lunin VV, Wernimont AK, Lew J, Wasney G, Kozieradzki I, Vedadi M, Bochkarev A, Arrowsmith CH, Sundstrom M, Weigelt J, Edwards AE, Hui R, Artz J, Amani M, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calcium/calmodulin-dependent protein kinase with a kinase domain and 4 calmodulin like EF hands Chains: A, B, D
Molecule details ›
Chains: A, B, D
Length: 294 amino acids
Theoretical weight: 34.09 KDa
Source organism: Cryptosporidium parvum Iowa II
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5CYL9 (Residues: 197-472; Coverage: 41%)
Gene name: cgd7_1840
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand SEP 3 x SEP

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: C2
Unit cell:
a: 138.178Å b: 86.476Å c: 87.965Å
α: 90° β: 96.37° γ: 90°
R-values:
R R work R free
0.224 0.22 0.286
Expression system: Escherichia coli

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