› 2qg5

X-ray diffraction
2.3Å resolution

Cryptosporidium parvum calcium dependent protein kinase cgd7_1840

Released:
DOI: 10.2210/pdb2qg5/pdb
PDB entry 2qg5 coloured by chain, front view.
PDB entry 2qg5 coloured by chain, side view.
PDB entry 2qg5 coloured by chain, top view.
Source organism: Cryptosporidium parvum Iowa II
Entry authors: Lunin VV, Wernimont AK, Lew J, Wasney G, Kozieradzki I, Vedadi M, Bochkarev A, Arrowsmith CH, Sundstrom M, Weigelt J, Edwards AE, Hui R, Artz J, Amani M, Structural Genomics Consortium (SGC)

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176948 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
non-specific serine/threonine protein kinase Chains: A, B, D
Molecule details ›
Chains: A, B, D
Length: 294 amino acids
Theoretical weight: 34.09 KDa
Source organism: Cryptosporidium parvum Iowa II
Expression system: Escherichia coli
UniProt:
  • Canonical: Q5CYL9 (Residues: 197-472; Coverage: 41%)
Gene name: cgd7_1840
Sequence domains: Protein kinase domain
Structure domains:

Ligands and Environments

No bound ligands
1 modified residue:
Ligand SEP 3 x SEP

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 17-ID
Spacegroup: C2
Unit cell:
a: 138.178Å b: 86.476Å c: 87.965Å
α: 90° β: 96.37° γ: 90°
R-values:
R R work R free
0.224 0.22 0.286
Expression system: Escherichia coli

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