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2.2 Angstrom Structure of the human ferrochelatase variant E343K with substrate bound

Source organism: Homo sapiens
Biochemical function: ferrochelatase activity
Biological process: heme biosynthetic process
Cellular component: not assigned

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GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00762
Domain description: Ferrochelatase
Occurring in:
  1. Ferrochelatase, mitochondrial
The deposited structure of PDB entry 2qd1 contains 4 copies of Pfam domain PF00762 (Ferrochelatase) in Ferrochelatase, mitochondrial. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR001015
Domain description: Ferrochelatase
Occurring in:
  1. Ferrochelatase, mitochondrial
IPR019772
Domain description: Ferrochelatase, active site
Occurring in:
  1. Ferrochelatase, mitochondrial
IPR033644
Domain description: Ferrochelatase, C-terminal
Occurring in:
  1. Ferrochelatase, mitochondrial
IPR033659
Domain description: Ferrochelatase, N-terminal
Occurring in:
  1. Ferrochelatase, mitochondrial

Structure domain

CATH CATH domain
3.40.50.1400
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: Rossmann fold
Occurring in:
  1. Ferrochelatase, mitochondrial
The deposited structure of PDB entry 2qd1 contains 8 copies of CATH domain 3.40.50.1400 (Rossmann fold) in Ferrochelatase, mitochondrial. Showing 2 copies in chain A.

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