PDBe 2qae

X-ray diffraction
1.9Å resolution

Crystal Structure Analysis of Trypanosoma cruzi Lipoamide dehydrogenase

Released:
Source organism: Trypanosoma cruzi
Entry authors: Werner C, Krauth-Siegel RL, Stubbs MT, Klebe G

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Dihydrolipoyl dehydrogenase Chains: A, B
Molecule details ›
Chains: A, B
Length: 468 amino acids
Theoretical weight: 49.46 KDa
Source organism: Trypanosoma cruzi
Expression system: Escherichia coli
UniProt:
  • Best match: P90597 (Residues: 10-477)
Gene name: LPD

Ligands and Environments


Cofactor: Ligand FAD 2 x FAD
No bound ligands

No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P212121
Unit cell:
a: 60.7Å b: 104.9Å c: 147.4Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.187 0.187 0.217
Expression system: Escherichia coli