Function and Biology

Ensemble refinement of the crystal structure of an EF-hand protein from Danio rerio Dr.36843

Source organism: Danio rerio
Biochemical function: metal ion binding
Biological process: regulation of long-term synaptic potentiation
Cellular component: synapse

Sequence families

Pfam Protein families (Pfam)
PF13499
Domain description: EF-hand domain pair
Occurring in:
  1. Secretagogin
The deposited structure of PDB entry 2q4u contains 2 copies of Pfam domain PF13499 (EF-hand domain pair) in Secretagogin. Showing 2 copies in chain A.

PF13202
Domain description: EF hand
Occurring in:
  1. Secretagogin
The deposited structure of PDB entry 2q4u contains 1 copy of Pfam domain PF13202 (EF hand) in Secretagogin. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002048
Domain description: EF-hand domain
Occurring in:
  1. Secretagogin
IPR018247
Domain description: EF-Hand 1, calcium-binding site
Occurring in:
  1. Secretagogin
IPR011992
Domain description: EF-hand domain pair
Occurring in:
  1. Secretagogin
IPR035798
Domain description: Secretagogin, EF-hand domain
Occurring in:
  1. Secretagogin

Structure domain

CATH CATH domain
1.10.238.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Recoverin; domain 1
Homology: EF-hand
Occurring in:
  1. Secretagogin
The deposited structure of PDB entry 2q4u contains 3 copies of CATH domain 1.10.238.10 (Recoverin; domain 1) in Secretagogin. Showing 3 copies in chain A.