X-ray diffraction
2.4Å resolution

Ancestral Corticiod Receptor in Complex with DOC


Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ancestral Corticiod Receptor Chain: A
Molecule details ›
Chain: A
Length: 249 amino acids
Theoretical weight: 28.94 KDa
Source organism: unidentified
Expression system: Escherichia coli
Structure domains: Retinoid X Receptor
Nuclear receptor subfamily 0 group B member 2 Chain: B
Molecule details ›
Chain: B
Length: 10 amino acids
Theoretical weight: 1.05 KDa
Source organism: Homo sapiens
Expression system: Not provided
  • Canonical: Q15466 (Residues: 18-27; Coverage: 4%)
Gene names: NR0B2, SHP

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P43212
Unit cell:
a: 78.995Å b: 78.995Å c: 112.467Å
α: 90° β: 90° γ: 90°
R R work R free
0.196 0.196 0.24
Expression systems:
  • Escherichia coli
  • Not provided