X-ray diffraction
2.25Å resolution

Structure and rearrangements in the carboxy-terminal region of SpIH channels

Source organism: Mus musculus

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assemblies composition:
homo tetramer
homo octamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 200 amino acids
Theoretical weight: 23.43 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
  • Canonical: O88703 (Residues: 443-640; Coverage: 23%)
Gene names: Bcng2, Hac1, Hcn2
Sequence domains: Cyclic nucleotide-binding domain
Structure domains:

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: I4
Unit cell:
a: 94.734Å b: 94.734Å c: 124.047Å
α: 90° β: 90° γ: 90°
R R work R free
0.209 0.209 0.261
Expression system: Escherichia coli BL21(DE3)