GO terms
Biochemical function:
Biological process:
- autosome genomic imprinting
- retrotransposon silencing by heterochromatin formation
- negative regulation of DNA methylation-dependent heterochromatin formation
- genomic imprinting
- chorionic trophoblast cell differentiation
- stem cell differentiation
- negative regulation of DNA-templated transcription
- negative regulation of gene expression, epigenetic
- epigenetic programing of female pronucleus
- methylation
- cell differentiation
- negative regulation of macromolecule metabolic process
- regulation of gene expression
- spermatogenesis
- male meiosis I
- DNA methylation-dependent heterochromatin formation
- obsolete DNA methylation
- DNA metabolic process
- placenta development
- negative regulation of transcription by RNA polymerase II
Cellular component:
Sequence families
Protein families (Pfam)
![The deposited structure of PDB entry 2pvc contains 3 copies of Pfam domain PF17980 (Cysteine rich ADD domain in DNMT3) in DNA (cytosine-5)-methyltransferase 3-like. Showing 1 copy in chain C [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/2pvc_1_A_Pfam_PF17980_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>2pvc</span> contains 3 copies of Pfam domain <span class='highlight'>PF17980 (Cysteine rich ADD domain in DNMT3)</span> in <span class='highlight'>DNA (cytosine-5)-methyltransferase 3-like</span>. Showing 1 copy in chain <span class='highlight'>C [auth A]</span>.")
InterPro annotations
IPR029063
Domain description:
S-adenosyl-L-methionine-dependent methyltransferase superfamily
Occurring in:
Occurring in:
CATH domain![The deposited structure of PDB entry 2pvc contains 3 copies of CATH domain 3.40.50.150 (Rossmann fold) in DNA (cytosine-5)-methyltransferase 3-like. Showing 1 copy in chain C [auth A].](https://www.ebi.ac.uk/pdbe/static/entry/2pvc_1_A_CATH_3.40.50.150_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>2pvc</span> contains 3 copies of CATH domain <span class='highlight'>3.40.50.150 (Rossmann fold)</span> in <span class='highlight'>DNA (cytosine-5)-methyltransferase 3-like</span>. Showing 1 copy in chain <span class='highlight'>C [auth A]</span>.")