X-ray diffraction
1.65Å resolution

Crystal Structure of the T. brucei enolase complexed with phosphonoacetohydroxamate (PAH), His156-out conformation


Function and Biology Details

Reaction catalysed:
2-phospho-D-glycerate = phosphoenolpyruvate + H(2)O
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Entry contents:
1 distinct polypeptide molecule
phosphopyruvate hydratase Chain: A
Molecule details ›
Chain: A
Length: 432 amino acids
Theoretical weight: 46.9 KDa
Source organism: Trypanosoma brucei
Expression system: Escherichia coli
  • Canonical: Q38BV6 (Residues: 1-429; Coverage: 100%)
Gene name: Tb10.70.4740
Sequence domains:
Structure domains:

Ligands and Environments

3 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: LNLS BEAMLINE D03B-MX1
Spacegroup: C2221
Unit cell:
a: 73.858Å b: 109.279Å c: 107.946Å
α: 90° β: 90° γ: 90°
R R work R free
0.167 0.165 0.203
Expression system: Escherichia coli