X-ray diffraction
2.2Å resolution

Crystal Structure of Anopheles gambiae D7R4-tryptamine complex

Source organism: Anopheles gambiae
Entry authors: Andersen JF, Mans BJ, Calvo E, Ribeiro JM

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
D7r4 protein Chain: A
Molecule details ›
Chain: A
Length: 145 amino acids
Theoretical weight: 17.1 KDa
Source organism: Anopheles gambiae
Expression system: Escherichia coli
  • Canonical: Q9BIH3 (Residues: 22-165; Coverage: 100%)
Gene names: D7r4, d7r4
Sequence domains: PBP/GOBP family
Structure domains: Pheromone/general odorant binding protein domain

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P43
Unit cell:
a: 63.101Å b: 63.101Å c: 42.596Å
α: 90° β: 90° γ: 90°
R R work R free
0.176 0.172 0.248
Expression system: Escherichia coli