› 2ppi

X-ray diffraction
2.4Å resolution

Structure of the BTB (Tramtrack and Bric a brac) domain of human Gigaxonin

Released:
DOI: 10.2210/pdb2ppi/pdb
PDB entry 2ppi coloured by chain, front view.
PDB entry 2ppi coloured by chain, side view.
PDB entry 2ppi coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Amos A, Turnbull AP, Tickle J, Keates T, Bullock A, Savitsky P, Burgess-Brown N, Debreczeni JE, Ugochukwu E, Umeano C, Pike ACW, Papagrigoriou E, Sundstrom M, Arrowsmith CH, Weigelt J, Edwards A, von Delft F, Knapp S, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190544 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gigaxonin Chain: A
Molecule details ›
Chain: A
Length: 144 amino acids
Theoretical weight: 16.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9H2C0 (Residues: 6-126; Coverage: 20%)
Gene names: GAN, GAN1, KLHL16
Sequence domains: BTB/POZ domain
Structure domains: Potassium Channel Kv1.1; Chain A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: I4122
Unit cell:
a: 75.664Å b: 75.664Å c: 167.632Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.282 0.281 0.296
Expression system: Escherichia coli

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