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Crystal Structure of TEP1r

Source organism: Anopheles gambiae
Biochemical function: protein binding
Biological process: defense response to symbiont
Cellular component: extracellular space

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GO terms

Sequence families

Pfam Protein families (Pfam)
PF07677
Domain description: A-macroglobulin receptor binding domain
Occurring in:
  1. Thioester-containing protein 1 allele R1
The deposited structure of PDB entry 2pn5 contains 1 copy of Pfam domain PF07677 (A-macroglobulin receptor binding domain) in Thioester-containing protein 1 allele R1. Showing 1 copy in chain A.

PF21412
Domain description: TEP1, second CUB domain
Occurring in:
  1. Thioester-containing protein 1 allele R1

PF07678
Domain description: A-macroglobulin TED domain
Occurring in:
  1. Thioester-containing protein 1 allele R1
The deposited structure of PDB entry 2pn5 contains 1 copy of Pfam domain PF07678 (A-macroglobulin TED domain) in Thioester-containing protein 1 allele R1. Showing 1 copy in chain A.

PF00207
Domain description: Alpha-2-macroglobulin family
Occurring in:
  1. Thioester-containing protein 1 allele R1
The deposited structure of PDB entry 2pn5 contains 1 copy of Pfam domain PF00207 (Alpha-2-macroglobulin family) in Thioester-containing protein 1 allele R1. Showing 1 copy in chain A.

PF07703
Domain description: Alpha-2-macroglobulin bait region domain
Occurring in:
  1. Thioester-containing protein 1 allele R1
The deposited structure of PDB entry 2pn5 contains 1 copy of Pfam domain PF07703 (Alpha-2-macroglobulin bait region domain) in Thioester-containing protein 1 allele R1. Showing 1 copy in chain A.

PF17789
Domain description: Macroglobulin domain MG4
Occurring in:
  1. Thioester-containing protein 1 allele R1
The deposited structure of PDB entry 2pn5 contains 1 copy of Pfam domain PF17789 (Macroglobulin domain MG4) in Thioester-containing protein 1 allele R1. Showing 1 copy in chain A.

PF17791
Domain description: Macroglobulin domain MG3
Occurring in:
  1. Thioester-containing protein 1 allele R1
The deposited structure of PDB entry 2pn5 contains 1 copy of Pfam domain PF17791 (Macroglobulin domain MG3) in Thioester-containing protein 1 allele R1. Showing 1 copy in chain A.

PF01835
Domain description: MG2 domain
Occurring in:
  1. Thioester-containing protein 1 allele R1
The deposited structure of PDB entry 2pn5 contains 1 copy of Pfam domain PF01835 (MG2 domain) in Thioester-containing protein 1 allele R1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR009048
Domain description: Alpha-macroglobulin, receptor-binding
Occurring in:
  1. Thioester-containing protein 1 allele R1
IPR036595
Domain description: Alpha-macroglobulin, receptor-binding domain superfamily
Occurring in:
  1. Thioester-containing protein 1 allele R1
IPR011625
Domain description: Alpha-2-macroglobulin, bait region domain
Occurring in:
  1. Thioester-containing protein 1 allele R1
IPR013783
Domain description: Immunoglobulin-like fold
Occurring in:
  1. Thioester-containing protein 1 allele R1
IPR019742
Domain description: Alpha-2-macroglobulin, conserved site
Occurring in:
  1. Thioester-containing protein 1 allele R1
IPR047565
Domain description: Alpha-macroglobulin-like, thiol-ester bond-forming region
Occurring in:
  1. Thioester-containing protein 1 allele R1
IPR041813
Domain description: Alpha-2-macroglobulin, TED domain
Occurring in:
  1. Thioester-containing protein 1 allele R1
IPR008930
Domain description: Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid
Occurring in:
  1. Thioester-containing protein 1 allele R1
IPR011626
Domain description: Alpha-macroglobulin-like, TED domain
Occurring in:
  1. Thioester-containing protein 1 allele R1
IPR001599
Domain description: Alpha-2-macroglobulin
Occurring in:
  1. Thioester-containing protein 1 allele R1
IPR040839
Domain description: Macroglobulin domain MG4
Occurring in:
  1. Thioester-containing protein 1 allele R1
IPR041555
Domain description: Macroglobulin domain MG3
Occurring in:
  1. Thioester-containing protein 1 allele R1
IPR002890
Domain description: Macroglobulin domain
Occurring in:
  1. Thioester-containing protein 1 allele R1

Structure domains

CATH CATH domains
2.60.120.1540
Class: Mainly Beta
Architecture: Sandwich
Topology: Jelly Rolls
Homology: Jelly Rolls
Occurring in:
  1. Thioester-containing protein 1 allele R1
The deposited structure of PDB entry 2pn5 contains 1 copy of CATH domain 2.60.120.1540 (Jelly Rolls) in Thioester-containing protein 1 allele R1. Showing 1 copy in chain A.
2.20.130.20
Class: Mainly Beta
Architecture: Single Sheet
Topology: S-adenosyl-L-methionine-dependent methyltransferases
Homology: S-adenosyl-L-methionine-dependent methyltransferases
Occurring in:
  1. Thioester-containing protein 1 allele R1
The deposited structure of PDB entry 2pn5 contains 1 copy of CATH domain 2.20.130.20 (S-adenosyl-L-methionine-dependent methyltransferases) in Thioester-containing protein 1 allele R1. Showing 1 copy in chain A.
2.60.40.10
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulins
Occurring in:
  1. Thioester-containing protein 1 allele R1
The deposited structure of PDB entry 2pn5 contains 2 copies of CATH domain 2.60.40.10 (Immunoglobulin-like) in Thioester-containing protein 1 allele R1. Showing 2 copies in chain A.
2.60.40.1930
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulin-like
Occurring in:
  1. Thioester-containing protein 1 allele R1
The deposited structure of PDB entry 2pn5 contains 2 copies of CATH domain 2.60.40.1930 (Immunoglobulin-like) in Thioester-containing protein 1 allele R1. Showing 2 copies in chain A.
2.60.40.690
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Alpha-macroglobulin, receptor-binding domain
Occurring in:
  1. Thioester-containing protein 1 allele R1
The deposited structure of PDB entry 2pn5 contains 1 copy of CATH domain 2.60.40.690 (Immunoglobulin-like) in Thioester-containing protein 1 allele R1. Showing 1 copy in chain A.
1.50.10.20
Class: Mainly Alpha
Architecture: Alpha/alpha barrel
Topology: Glycosyltransferase
Homology: Glycosyltransferase
Occurring in:
  1. Thioester-containing protein 1 allele R1
The deposited structure of PDB entry 2pn5 contains 1 copy of CATH domain 1.50.10.20 (Glycosyltransferase) in Thioester-containing protein 1 allele R1. Showing 1 copy in chain A.
2.60.40.1940
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulin-like
Occurring in:
  1. Thioester-containing protein 1 allele R1
The deposited structure of PDB entry 2pn5 contains 1 copy of CATH domain 2.60.40.1940 (Immunoglobulin-like) in Thioester-containing protein 1 allele R1. Showing 1 copy in chain A.
2.60.40.2950
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Immunoglobulin-like
Occurring in:
  1. Thioester-containing protein 1 allele R1
The deposited structure of PDB entry 2pn5 contains 1 copy of CATH domain 2.60.40.2950 (Immunoglobulin-like) in Thioester-containing protein 1 allele R1. Showing 1 copy in chain A.

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