PDBe 2pm1

X-ray diffraction
1.6Å resolution

Derivative of human alpha-defensin 1 (HNP1)

Released:
Source organism: Homo sapiens
Entry authors: Lubkowski J, Pazgier M, Lu W

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neutrophil defensin 1 Chain: A
Molecule details ›
Chain: A
Length: 30 amino acids
Theoretical weight: 3.28 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P59665 (Residues: 65-94; Coverage: 40%)
Gene names: DEF1, DEFA1, DEFA1B, DEFA2, MRS
Sequence domains: Mammalian defensin

Ligands and Environments

No bound ligands

1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-BM
Spacegroup: P3121
Unit cell:
a: 38.811Å b: 38.811Å c: 31.56Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.154 0.151 0.201
Expression system: Escherichia coli