2pkt

X-ray diffraction
1.5Å resolution

Crystal structure of the human CLP-36 (PDLIM1) bound to the C-terminal peptide of human alpha-actinin-1

Released:
Source organism: Homo sapiens
Entry authors: Uppenberg J, Gileadi C, Elkins J, Bray J, Burgess-Brown N, Salah E, Gileadi O, Bunkoczi G, Ugochukwu E, Umeano C, von Delft F, Weigelt J, Arrowsmith CH, Edwards A, Sundstrom M, Doyle DA, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
PDZ and LIM domain protein 1 Chain: A
Molecule details ›
Chain: A
Length: 91 amino acids
Theoretical weight: 9.73 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O00151 (Residues: 1-87; Coverage: 26%)
Gene names: CLIM1, CLP36, PDLIM1
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments


No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P6522
Unit cell:
a: 38.74Å b: 38.74Å c: 246.46Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.213 0.212 0.231
Expression system: Escherichia coli BL21(DE3)