2ph9

X-ray diffraction
2.88Å resolution

Galanthamine bound to an ACh-binding Protein

Released:
Source organism: Aplysia californica
Entry authors: Hansen SB, Taylor P

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo pentamer (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neur_chan_LBD domain-containing protein Chains: A, B, C, D, E
Molecule details ›
Chains: A, B, C, D, E
Length: 230 amino acids
Theoretical weight: 26.21 KDa
Source organism: Aplysia californica
Expression system: Homo sapiens
UniProt:
  • Canonical: Q8WSF8 (Residues: 18-236; Coverage: 100%)
Sequence domains: Neurotransmitter-gated ion-channel ligand binding domain
Structure domains: Neurotransmitter-gated ion-channel ligand-binding domain

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.2.1
Spacegroup: C2221
Unit cell:
a: 143.95Å b: 145.472Å c: 143.555Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.207 0.205 0.237
Expression system: Homo sapiens